Studies of Oral Vaccination against Infectious Pancreatic Necrosis in Atlantic salmon:
Focus on Antigen Production, Antigen Kinetics, and Immune Responses
Studier av oral vaksinering mot infeksiøs pankreas nekrose hos atlantisk laks: Fokus på antigen produksjon, antigen kinetikk, og immunrespons
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Contents
1 Acknowledgements ... 1
2 Summary ... 2
3 Sammendrag... 4
4 Acronyms/Abbreviations ... 5
5 Papers ... 7
6 Introduction ... 8
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8 Methodology ... 22
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12 Perspectives ... 42
Reference List ... 43
1 Acknowledgements
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2 Summary
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3 Sammendrag
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4 Acronyms/Abbreviations
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9 Summary of separate papers
Paper I: Delayed protein shut down and cytopathic changes lead to high yields of infectious pancreatic necrosis virus cultured in Asian Grouper cells
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Paper II: IPNV antigen uptake and distribution in Atlantic salmon following oral administration
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Paper III: Augmentation of the antibody response of Atlantic salmon by oral administration of alginate-encapsulated IPNV antigens
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10 Results and Discussion 10.1 Overview
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10.2 High yield of infectious pancreatic necrosis virus produced by Asian grouper cell strain K (AGK)
10.2.1 The effects at cell population level
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10.5 The immune responses following oral vaccination with IPNV in Atlantic salmon
10.5.1 The systemic humoral responses
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11 Conclusion Antigen production
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