Seqüência de Aminoácidos das Principais Proteínas
A seguir apresentam-se as estruturas primárias das principais proteínas do soro apresentadas na literatura obtidas da Protein Data Bank.
SEQÜÊNCIA DE α-LACTALBUMINA
GLU-GLN-LEU-THR-LYS-CYS-GLU-VAL-PHE-GLN-LYS-LEU-LYS-ASP-LEU-LYS- ASP-TYR-GLY-GLY-VAL-SER-LEU-PRO-GLU-TRP-VAL-CYS-THR-ALA-PHE-HIS- THR-SER-GLY-TYR-ASP-THR-GLN-ALA-ILE-VAL-GLN-ASN-ASN-ASP-SER-THR- GLU-TYR-GLY-LEU- PHE-GLN-ILE-ASN-ASN-LYS-ILE-TRP-CYS-LYS-ASP-ASP- GLN ASN-PRO-HIS-SER-ARG-ASN-ILE-CYS-ASN-ILE-SER-CYS-ASP LYS-PHE-LEU- ASP-ASP-ASP-LEU-THR-ASP-ASP-ILE-VAL-CYS ALA-LYS-LYS-ILE-LEU-ASP-LYS- VAL-GLY-ILE-ASN-TYR-TRPLEU-ALA-HIS-LYS-ALA-LEU-CYS-SER-GLU-LYS-
LEU-ASP-LN TRP-LEU-CYS-GLU-LYS-LEU
SEQÜÊNCIA DE β-LACTOGLOBULINA
LEU-ILE-VAL-THR-GLN-THR-MET-LYS-GLY-LEU-ASP-ILE-GLN LYS-VAL-ALA- GLY-THR-TRP-TYR-SER-LEU-ALA-MET-ALA-ALA-SER-ASP-ILE-SER-LEU-LEU- ASP-ALA-GLN-SER-ALA-PRO-LEUARG-VAL-TYR-VAL-GLU-GLU-LEU-LYS-PRO- THR-PRO-GLU-GLY-ASP-LEU-GLU-ILE-LEU-LEU-GLN-LYS-TRP-GLU-ASN-GLY- GLU-CYS-ALA-GLN-LYS-LYS-ILE-ILE-ALA-GLU-LYS-THR-LYS-ILE-PRO-ALA- VAL-PHE-LYS-ILE-ASP-ALA-LEU-ASN-GLU-ASN-LYS VAL-LEU-VAL-LEU-ASP- THR-ASP-TYR-LYS-LYS-TYR-LEU-LEU-PHE-CYS-MET-GLU-ASN-SER-ALA-GLU- PRO-GLU-GLN-SER-LEU VAL-CYS-GLN-CYS-LEU-VAL-ARG-THR-PRO-GLU-VAL- ASP-ASP-GLU-ALA-LEU-GLU-LYS-PHE-ASP-LYS-ALA-LEU-LYS-ALA-LEU PRO- MET-HIS-ILE-ARG-LEU-SER-PHE-ASN-PRO-THR-GLN-LEU-GLU-GLU-GLN-CYS- HIS-ILE
SEQÜÊNCIA DA SORO ALBUMINA BOVINA
ASP- THR- HIS- LYS- SER- GLU- ILE- ALA- HIS- ARG- PHE- LYS- ASP- LEU- GLY- GLU- GLU- HIS- PHE- LYS- GLY- LEU- VAL- LEU- ILE- ALA- PHE- SER- GLN- TYR- LEU-
GLN- GLN- CYS- PRO- PHE- ASP- GLU- HIS- VAL- LYS- LEU- VAL- ASN- GLU-
LEU- THR- GLU- PHE- ALA- LYS- THR- CYS- VAL- ALA- ASP- GLU- SER- HIS- ALA- GLY- CYS- GLU- LYS- SER- LEU- HIS- THR- LEU- PHE- GLY- ASP- GLU- LEU- CYS-
LYS- VAL- ALA- SER- LEU- ARG- GLU- THR- TYR- GLY- ASP- MET- ALA- ASP- CYS- CYS- GLU- LYS- GLN- GLU- PRO- GLU- ARG- ASN- GLU- CYS- PHE- LEU- SER- HIS- LYS- ASP- ASP- SER- PRO- ASP- LEU- PRO- LYS- LEU- LYS- PRO- ASP- PRO- ASN- THR- LEU- CYS- ASP- GLU- PHE- LYS- ALA- ASP- GLU- LYS- LYS- PHE- TRP- GLY- LYS- TYR- LEU- TYR- GLU- ILE- ALA- ARG- ARG- HIS- PRO- TYR- PHE- TYR- ALA- PRO- GLU- LEU- LEU- TYR- TYR- ALA- ASN- LYS- TYR- ASN- GLY- VAL- PHE- GLN- GLU- CYS- CYS- GLN- ALA- GLU- ASP- LYS- GLY- ALA- CYS-
LEU- LEU- PRO- LYS- ILE- GLU- THR- MET- ARG- GLU- LYS- VAL- LEU- THR-
SER- SER- ALA- ARG- GLN- ARG- LEU- ARG- CYS- ALA- SER- ILE- GLN- LYS- PHE- GLY- GLU- ARG- ALA- LEU- LYS- ALA- TRP- SER- VAL- ALA- ARG- LEU- SER- GLN- LYS- PHE- PRO- LYS- ALA- GLU- PHE- VAL- GLU- VAL- THR- LYS- LEU- VAL- THR- ASP- LEU- THR- LYS- VAL- HIS- LYS- GLU- CYS- CYS- HIS- GLY- ASP-
LEU- LEU- GLU- CYS- ALA- ASP- ASP- ARG- ALA- THR- LEU- ALA- LYS- TYR- ILE-
CYS- ASP- ASN- GLN- ASP- THR- ILE- SER- SER- LYS- LEU- LYS- GLU- CYS- CYS- ASP-
LYS- PRO- LEU- LEU- GLU- LYS- SER- HIS- CYS- ILE- ALA- GLU- VAL- GLU- LYS- ASP- ALA- ILE- PRO- GLU- ASP- LEU- PRO- PRO- LEU- THR- ALA- ASP- PHE- ALA- GLU- ASP- LYS- ASP- VAL- CYS- LYS- ASN- TYR- GLN- GLU- ALA- LYS- ASP- ALA- PHE- LEU- GLY- SER- PHE- LEU- TYR- GLU- TYR- SER- ARG- ARG- HIS- PRO- GLU- TYR- ALA- VAL- SER- VAL- LEU- LEU- ARG- LEU- ALA- LYS- GLU- TYR- GLU- ALA- THR- LEU- GLU- GLU- CYS- CYS- ALA- LYS- ASP- ASP- PRO- HIS- ALA- CYS- TYR- THR- SER- VAL- PHE- ASP- LYS- LEU- LYS- HIS- LEU- VAL- ASP- GLU- PRO- GLN- ASN- LEU- ILE- LYS- GLN- ASN- CYS- ASP- GLN- PHE- GLU- LYS- LEU- GLY- GLU- TYR- GLY- PHE- GLN- ASN- ALA- LEU- ILE- VAL- ARG- TYR- THR-
ARG- LYS- VAL- PRO- GLN- VAL- SER- THR- PRO- THR- LEU- VAL- GLU- VAL- SER- ARG- SER- LEU- GLY- LYS- VAL- GLY- THR- ARG- CYS- CYS- THR- LYS- PRO- GLU- SER- GLU- ARG- MET- PRO- CYS- THR- GLU- ASP- TYR- LEU- SER-
LEU- ILE- LEU- ASN- ARG- LEU- CYS- VAL- LEU- HIS- GLU- LYS- THR- PRO- VAL- SER- GLU- LYS- VAL- THR- LYS- CYS- CYS- PRO- GLU- SER- LEU- VAL- ASN-
ARG- ARG- PRO- CYS- PHE- SER- ALA- LEU- THR- PRO- ASP- GLU- THR- TYR-
VAL- PRO- LYS- ALA- PHE- ASP- GLU- LYS- LEU- PHE- THR- PHE- HIS- ALA- ASP- ILE- CYS- THR- LEU- PRO- ASP- THR- GLU- LYS- GLN- ILE- LYS- LYS- GLN- THR- ALA- LEU- VAL- GLU- LEU- LEU- LYS- HIS- LYS- PRO- LYS- ALA- THR- GLU- GLU- GLN- LEU- LYS- THR- VAL- MET- GLU- ASN- PHE- VAL- ALA- PHE- VAL- ASP- LYS- CYS- CYS- ALA- ALA- ASP- ASP- LYS- GLU- ALA- CYS- PHE- ALA- VAL- GLU- GLY- PRO- LYS- LEU- VAL- VAL- SER- PRO- GLN- THR- ALA- LEU- ALA-
Tabela A2.1: Conteúdo teórico de cada aminoácido para as principais proteínas do soro de queijo
Aminoácidos α-Lactalbumina β-Lactoglobulina Soro Albumina
Bovina (SAB) Triptofano, Trp, W 4 2 2 Isoleucina, Ileu, I, 8 10 14 Fenilalanina, Phe, F 4 4 27 Prolina, Pro, P 2 8 30 Tyrosina, Tyr, Y 4 4 20 Leucina, Leu. L 13 22 61 Valina, Val, V 6 10 36 Metionina, Met, M 0 4 4 Lisina, Lys, K 13 15 59 Cisteína, Cys, C 8 5 35 Alanina, Ala, A 5 14 46 Histidina, His, H 3 2 17 Arginina, Arg, R 1 3 23 Glutamato, Glu, E 6 16 59 Aspartato, Asp, D 14 10 40 Glicina, Gly, G 5 4 16 Asparagina, Asn, N 8 5 13 Serina, Ser, S 6 7 28 Treonina, Thr, T 6 8 33 Glutamina, Gln, Q 6 9 20