• No results found

ability to understand the basis of these differences. The UNPD and USCB predict adult mortality from under-5 mortality in many lower-SDI countries, which might be a contributing factor. The UNPD and USCB use model life table systems based on a set of life tables collected before 1980; there are many reasons to expect that these mortality patterns are not relevant to the current period.

96,97

Limitations

Although this study includes many methodological

advances, it also has limitations. First, the accuracy of the

estimates depends crucially on the available data sources

and density of data by time period. For child mortality, at

least one year of data was available for all countries. For

adults, however, there were 12 countries with no data; in

these cases, estimates depend critically on covariates and

the ST-GPR statistical model. Additionally, for

country-years with input data, data quality, as determined by both

sampling and non-sampling errors, varies across

locations and over time within the same location. This

adds to the uncertainty in comparing the same metric

from different locations, even though we have made

every effort to systematically propagate uncertainty

throughout our estimation process. Second, for many

countries with limited or absent VR systems, particularly

in sub-Saharan Africa, we use sibling history data to

estimate levels and trends in adult mortality. Sibling

history data have several known biases.

17,22,98

In settings

outside of sub-Saharan Africa we found no net biases in

our estimates based on sibling histories when compared

with equivalent estimates derived from other sources of

information such as VR systems. Although differences

in adoption practices in parts of sub-Saharan Africa

create the potential for sibling histories to perform

differently than in other settings, Obermeyer and

colleagues,

25

Helleringer and colleagues,

98

and

Masquelier

99

did not find a consistent direction of bias in

sibling history data in these settings. Third, our

assessment of mortality depends on the validity of our

modelling of HIV/AIDS epidemics, particularly in

settings such as in eastern and southern sub-Saharan

Africa, which have large generalised epidemics. While

there are relatively robust data available on the prevalence

of HIV/AIDS from population-based surveys in many of

these countries, such data are often available only for

selected years, and the data on HIV/AIDS-specific

mortality and CD4 progression rates, both on and off

ART, are far more scarce. Death rates on ART by

CD4 count are also confounded by other indications for

ART such as the presence of opportunistic infections.

100–102

All combined, there is a much higher level of uncertainty

in the HIV/AIDS-specific mortality estimates than in

all-cause mortality estimation and these are used as a key

(Figure 9 continues on next page) Czech Republic

Cyprus Cuba Croatia Côte d’Ivoire Costa Rica Congo (Brazzaville) Comoros Colombia China Chile Chad Central African Republic Cape Verde Canada Cameroon Cambodia Burundi Burkina Faso Bulgaria Brunei Brazil Botswana Bosnia and Herzegovina Bolivia Bhutan Bermuda Benin Belize Belgium Belarus Barbados Bangladesh Bahrain Azerbaijan Austria Australia Armenia Argentina Antigua and Barbuda Angola Andorra American Samoa Algeria Albania Afghanistan

–10 0 10

Difference in life expectancy at birth (GBD 2016 minus indicated estimate, years) US Census Bureau

Significant Not significant World Population Prospects 2017 WHO

Males Females

(Figure 9 continues on next page) Kuwait

Kiribati Kenya Kazakhstan Jordan Japan Jamaica Italy Israel Ireland Iraq Iran Indonesia India Iceland Hungary Honduras Haiti Guyana Guinea-Bissau Guinea Guatemala Guam Grenada Greenland Greece Ghana Germany Georgia Gabon France Finland Fiji Federated States of Micronesia Ethiopia Estonia Eritrea Equatorial Guinea El Salvador Egypt Ecuador Dominican Republic Dominica Djibouti Denmark DR Congo

–10 0 10

Difference in life expectancy at birth (GBD 2016 minus indicated estimate, years) US Census Bureau

Significant Not significant World Population Prospects 2017 WHO

Males Females

Portugal Poland Philippines Peru Paraguay Papua New Guinea Panama Palestine Pakistan Oman Norway Northern Mariana Islands North Korea Nigeria Niger Nicaragua New Zealand Netherlands Nepal Namibia Myanmar Mozambique Morocco Montenegro Mongolia Moldova Mexico Mauritius Mauritania Marshall Islands Malta Mali Maldives Malaysia Malawi Madagascar Macedonia Luxembourg Lithuania Libya Liberia Lesotho Lebanon Latvia Laos Kyrgyzstan

–10 0 10

Difference in life expectancy at birth (GBD 2016 minus indicated estimate, years) US Census Bureau

Significant Not significant World Population Prospects 2017 WHO

Males Females

(Figure 9 continues on next page)

United Arab Emirates Ukraine Uganda Turkmenistan Turkey Tunisia Trinidad and Tobago Tonga Togo Timor-Leste The Gambia The Bahamas Thailand Tanzania Tajikistan Taiwan (Province of China) Syria Switzerland Sweden Swaziland Suriname Sudan Sri Lanka Spain South Sudan South Korea South Africa Somalia Solomon Islands Slovenia Slovakia Singapore Sierra Leone Seychelles Serbia Senegal Saudi Arabia São Tomé and Príncipe Samoa Saint Vincent and the Grenadines Saint Lucia Rwanda Russia Romania Qatar Puerto Rico

–10 0 10

Difference in life expectancy at birth (GBD 2016 minus indicated estimate, years) US Census Bureau

Significant Not significant World Population Prospects 2017 WHO

Males Females

(Figure 9 continues on next page)

covariate in the estimation of all-cause mortality. Fourth, there is significant challenge in the synthesis of stillbirth mortality across countries, because the definition of stillbirth varies over time and across countries. We include a fixed effect on the definition of stillbirth with a no definition category. Bias adjustment for data from this definition category is done with the adjustment factor used by Blencowe and colleagues.

23

Although this situation is not ideal, it does help us to generate estimates for countries in central Asia where no definition of stillbirth is provided in the data that we have. Fifth, in this assessment we use the UNPD estimates of population by age, sex, and year in 150 countries.

However, in years far from a census, these estimates of