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Genetic drift scenarios simulated with a coalescent backward approach in SIMCOAL2, assuming a founder population of Ne

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Genetic drift scenarios simulated with a coalescent backward approach in SIMCOAL2, assuming a founder population of Ne = 300 splitting into five populations of Ne = 60 and constant size, 20 generations ago. We simulated independent chromosomes and a mutation rate of 10-4 in an IAM model constrained to 15 alleles. The right column states the proportion of pairwise comparisons that is significant after correction for multiple tests. Ten independent simulations of three migration rates (m = 0.05; 0.1; 0.2) revealing comparable FST’s with observed values are given below.

Migration Mean pairwise FST (θ) ± SD P % P < 0.05 % Sign. FDR

0,01 0,0675 0,0106 < 0,0001 100 100

0,05 (a) 0,0126 0,0038 < 0,0113 100 100

0,1 (b) 0,0048 0,0026 < 0,3902 50 27

0,2 (c) 0,0021 0,0024 < 0,8077 18 6

0,3 0,0030 0,0032 < 0.9219 30 10

0,4 0,0008 0,0019 < 0.9824 10 0

0,5 0,0007 0,0011 < 0.9727 0 0

0,99 0,0020 0,0020 < 0.9121 0 0

* a,b,c; mean over 10 simulations (below)

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