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iRefIndex : Interaction Reference Index : International Conference on Intelligent Systems for Molecular Biology (ISMB), Stockholm, Sweden, June 27-July 02, 2009 : Poster E29

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UNIVERSITY OF OSLO

Department of Informatics

International Conference on Intelligent Systems for Molecular Biology(ISMB) Stockholm, Sweden:

(June 27 – July 02, 2009) Poster:E29

Research Report No:400

Sabry Razick Ian M Donaldson

ISBN: 82-7368-361-3

September 2010

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iRefIndex: Interaction Reference Index

Sabry Razick1,2 and Ian M Donaldson 1,3

1The Biotechnology Centre of Oslo, University of Oslo, P.O. Box 1125 Blindern, 0317 Oslo, Norway

Biomedical Research Group, Department of Informatics, University of Oslo, P.O. Box 1080 Blindern,  0316 Oslo, Norway

Department for Molecular Biosciences, University of Oslo, P.O. Box 1041 Blindern, 0316 Oslo, Norway

iRefIndex provides an index of protein interactions available in a number of primary interaction  databases. This index allows the user to search for a protein and retrieve a non­redundant list of  interactors for that protein.

This system uses the Redundant Object Group (ROG) and Redundant Interaction Group (RIG)  identifier to group proteins and interactions into redundant groups. This method allows users to  integrate their own data with the iRefIndex in a way that ensures proteins with the exact same  sequence and NCBI taxonomy identifier will be represented only once.

iRefIndex has consolidated 10 different interaction databases using this method and provides a 

number of methods to access these data. This includes downloading as PSI­MI compliant tab­delimited  file and from the iRefScape plugin for (http://www.cytoscape.org/), PSICQUIC web services  and the  iRefWeb(http://wodaklab.org/iRefWeb/).

More details about iRefIndex and links available at: http://irefindex.uio.no/wiki/iRefIndex

This poster was published in the ISMB (International Conference on Intelligent Systems for Molecular  Biology) conference 2009 (http://www.iscb.org/ismbeccb2009/index.php).

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