A Computational Analysis of Motif-Negative VDR-DNA Interaction and Possible Explanations of Its Mechanism of Interaction

DNAse I footprinting Computational analysis of TF binding sites Context and aims of the study VDR binds to an RXR-VDR-like motif VDR binds in HOT (High Occupancy of Transcription Factor) regions Differences in enriched DNA feature regions in VDR- positive versus negative Motif position distribution Suggestions for future work