Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial

Therefore, we designed a double-blind, placebo-controlled, parallel-group RCT to evaluate the short-term effectiveness of zopiclone on self-reported sleep quality in patients

For scientific purposes: glucose, white cell counts and C-reactive protein (CRP) for further safety monitoring and evaluation of inflammatory mechanisms and genetics/epigenetics;

In this study, none of the four primary potential ef- fect modifiers (type I Modic changes, previous disc surgery, positive pain provocation test, high CRP) had a clinically relevant

Asgeir Johannessen, MD PhD, Department of Infectious Diseases, Vestfold Hospital Trust, Tønsberg, Norway, Institute of Clinical Medicine, University of Oslo, Oslo, Norway..

Background: The objectives of this study are to determine the effects of regularly scheduled administration of paracetamol (acetaminophen) on quality of life (QoL), discomfort, pain

This paper presents the design of the BackToBasic study, where we will assess the effect of an anti- inflammatory treatment versus placebo in patients with chronic low back pain

The adjusted mean treatment differences in change from baseline in 0e4 h serial FEV 1 on days 1 and 28 were higher for the FF/VI group compared with the placebo group at all