RESEARCH ARTICLE

HK, 3 hydroxykynurenine; HKr, ratio of HK to (KA + XA + AA + HAA); HUSK, Hordaland Health Study; KA, kynurenic acid; KTR, kynurenine:Trp ratio; Kyn, kynurenine; PLP, pyridoxal 5

4 Abbreviations used: AA, anthranilic acid; CRP, C-reactive protein; eGFR, estimated glomerular filtration rate; GAM, generalized additive model; HAA,

Thus, plasma concentrations of creatine, cystathionine, kynurenic acid, and 3-hydroxykynurenine jointly reveal effects of vitamin B-6 restriction on the profiles of one-carbon

Main findings: Higher kynurenine to tryptophan ratio (KTR) and neopterin concentrations were linearly associated with lower cognitive test performance, whereas kynurenine (Kyn) had

Plasma GDF-15 associates with poor survival, also in low-risk patients To validate previous observations that plasma level of GDF-15 is a biomarker for poor progno- sis in

It has previously been shown that pretreatment of differentiated human skeletal muscle cells (myotubes) with eicosapentaenoic acid (EPA) promoted increased uptake of fatty acids

A few, smaller human in vivo studies have explored placental and fetal AA uptake and release under normal physiological conditions by measuring plasma concen- trations and

Here we report a comprehensive analysis of serum concentrations of amino acids, including metabolites of tryptophan, the kynurenine pathway and vitamin B6 in a well